Marialuisa Sensi’s main research interests at Fondazione IRCCS Istituto Nazionale dei Tumori concerned the field of immunology and molecular biology of cutaneous melanoma. Within these areas, she identified novel melanoma antigens specifically recognized by T cells of melanoma patients and deeply studied the diversity of the T cell receptor repertoire expressed by tumor-specific T lymphocytes. In order to understand molecular pathways that influence the heterogeneity and the therapeutic response of this disease, more recently, she shifted her research focus on genomic technologies and computational biology.
Her current position is head of the Platform of Integrated Biology, an Institutional Core Facility for Genomics and Bioinformatics at the Department of Applied Research and Tecnology Development that provides technological support to translational oncology and carries out independent research. During her professional career she worked at the Immunobiology Research Center of the University of Minnesota, Minneapolis, USA and at the Basel Institute of Immunology, Basel, Switzerland. She is author and co-author of over 90 peer-reviewed publications in basic and translational research (h-index 24).